General description
Black pepper (Piper nigrum) is one of the most used spices in the world. It contains a chemical called piperine, which appears to kill bacteria.
Piperine can also kill fungus andparasitesand help the body absorb some medications. Black pepper and white pepper come from the same plant species, but are produced differently. Black pepper is made by cooking the dried and unripe fruit. White pepper is made by cooking and drying the ripe seeds.
People take black pepper tobocaforallergic rhinitis,asma,stomach ache, and many other conditions, but there is not good scientific evidence to support these uses.
Uses and effectiveness?
At the moment we have no information about BLACK PEPPER AND WHITE PEPPERgeneral description.
Secundary effects
when it is taken byboca: Black pepper is commonly consumed in food. There is not enough reliable information to know whether using large amounts of black pepper as a medicine is safe.
When applied tocoat: Black pepper oil is possibly safe. It is generally well tolerated, but if you get intoeyescan burn Some people may develop aallergyto black pepper.
when inhaled: Black pepper oil is possibly safe when used short-term. It may have a burnt aftertaste and may alter thestomach. could also causefor % s.
special precautionsand notices
when it is taken byboca: Black pepper is commonly consumed in food. There is not enough reliable information to know whether using large amounts of black pepper as a medicine is safe.
When applied tocoat: Black pepper oil is possibly safe. It is generally well tolerated, but if you get intoeyescan burn Some people may develop aallergyto black pepper.
when inhaled: Black pepper oil is possibly safe when used short-term. It may have a burnt aftertaste and may alter thestomach. could also causefor % s.the pregnancy: Black pepper is commonly consumed in food. But it is probably not safe when taken in large amounts during pregnancy. could cause aabortion. There is not enough reliable information available to know whether to apply black pepper tocoatis it safe or what the side effects might be.
mommy-feeding: Black pepper is commonly consumed in food. There is not enough reliable information to know whether black pepper is safe when used as a medicine while breastfeeding. Stay on the safe side and stick to food amounts.
Children: Black pepper is probably safe when ingested in food. It is possibly dangerous when ingested in large amounts. Deaths of children have been reported due to the accidental entry of large amounts of black pepper into thelungs. There is not enough reliable information available to know whether to apply black pepper oil to thecoatit is safe for children.
bleeding conditions: Piperine, a chemical in black pepper, may slow downbloodclotting Taking black pepper in larger amounts than food may increase the risk of bleeding in people withbleeding disorders.
Surgery: Ingesting black pepper in greater amounts than food can cause bleeding complications or affectblood sugar levelsduring surgery. Do not take black pepper in larger amounts than food 2 weeks before surgery.
interactions?
Lithium interacts with BLACK PEPPER AND WHITE PEPPER
Taking black pepper can decrease how well the body gets rid of lithium. This can increase the amount of lithium in the body and cause serious side effects. Talk to your doctor before using this product if you are taking lithium. Your lithium dose may need to be changed.
Liver modified drugs (cytochrome P450 3A4 (CYP3A4) substrates) interact with BLACK PEPPER AND WHITE PEPPER
The liver changes and breaks down some drugs. Black pepper can change how quickly the liver breaks down these drugs. This can change the effects and side effects of these medications.
Drugs driven by cell pumps (P-glycoprotein substrates) interact with BLACK PEPPER AND WHITE PEPPER
Some drugs are moved in and out of cells by means of pumps. Black pepper can change how these pumps work and change the amount of medicine that stays in the body. In some cases, this can change the effects and side effects of a medication.
Phenytoin (Dilantin) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase the amount of phenytoin absorbed by the body. Taking black pepper along with phenytoin may increase the effects and side effects of phenytoin.
Propranolol (Inderal) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase the amount of propranolol absorbed by the body. Taking black pepper along with propranolol may increase the effects and side effects of propranolol.
Rifampicin (Rifadin) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase the amount of rifampicin absorbed by the body. Taking black pepper along with rifampicin may increase the effects and side effects of rifampicin.
Theophylline interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase the amount of theophylline absorbed by the body. This can cause an increase in theophylline effects and side effects.
Medicines that slow blood clotting (Anticoagulants / Antiplatelet drugs) interact with BLACK PEPPER AND WHITE PEPPER
Black pepper can slow blood clotting. Taking black pepper along with medications that also slow blood clotting can increase your risk of bruising and bleeding.
Medications for diabetes (antidiabetic drugs) interact with BLACK PEPPER AND WHITE PEPPER
Black pepper can lower blood sugar levels. Taking black pepper along with diabetes medications can cause your blood sugar to drop too low. Monitor your blood sugar closely.
Ciclosporin (Neoral, Sandimmune) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase cyclosporine levels in the body. Taking black pepper with cyclosporine may increase the effects and side effects of cyclosporine. But it's not clear if this is a big concern.
Liver modified drugs (cytochrome P450 1A1 (CYP1A1) substrates) interact with BLACK PEPPER AND WHITE PEPPER
The liver changes and breaks down some drugs. Black pepper can change how quickly the liver breaks down these drugs. This can change the effects and side effects of these medications.
Liver modified drugs (cytochrome P450 2B1 (CYP2B1) substrates) interact with BLACK PEPPER AND WHITE PEPPER
The liver changes and breaks down some drugs. Black pepper can change how quickly the liver breaks down these drugs. This can change the effects and side effects of these medications.
Liver modified drugs (cytochrome P450 2D6 (CYP2D6) substrates) interact with BLACK PEPPER AND WHITE PEPPER
The liver changes and breaks down some drugs. Black pepper can change how quickly the liver breaks down these drugs. This can change the effects and side effects of these medications.
Nevirapine (Viramune) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase nevirapine levels in the body. Taking black pepper with nevirapine may increase the effects and side effects of nevirapine. But it's not clear if this is a big concern.
Pentobarbital (Nembutal) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase drowsiness caused by pentobarbital. Taking black pepper with pentobarbital can increase the sedative side effects of pentobarbital.
Atorvastatin (Lipitor) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase blood levels of atorvastatin. Taking black pepper with atorvastatin may increase the effects and side effects of atorvastatin.
moderate interaction
Be careful with this combination.
Carbamazepine (Tegretol) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase the amount of carbamazepine absorbed by the body. This can increase the chance of side effects. But it's not clear if this is a big concern.
Amoxicillin (Amoxil, Trimox) interacts with BLACK PEPPER AND WHITE PEPPER
Black pepper can increase blood levels of amoxicillin. Taking black pepper with amoxicillin may increase the effects and side effects of amoxicillin. But it's not clear if this is a big concern.
minor interaction
Beware of this combination
dosage
Black pepper is one of the most used spices in the world and is regularly consumed in food. But as a medicine, there is not enough reliable information to know what the proper dose of black pepper might be. Keep in mind that natural products aren't always necessarily safe, and dosages can be significant. Be sure to follow the relevant instructions on product labels and consult ahealth careprofessional before use.
Black pepper essential oil is commonly used inaromatherapy. Adults usually inhale the oil for 1-2 minutes at a time.
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TERMS OF USE AND IMPORTANT INFORMATION:This information is intended to supplement, not replace the advice of your physician or healthcare professional, and is not intended to cover all possible uses, precautions, interactions, or adverse effects. This information may not apply to your specific health circumstances. Never delay or ignore seeking professional medical advice from your physician or other qualified healthcare provider because of something you read on WebMD. You should always speak with your physician or healthcare professional before starting, stopping or changing any prescribed part of your treatment or health plan and to determine which course of therapy is right for you.
This copyrighted material is provided by the consumer version of the Natural Medicines Comprehensive Database. Information from this source is evidence-based and objective and without commercial influence. For professional medical information on natural medicines, check out the professional version of the Natural Medicines Comprehensive Database.
© Faculty of Therapeutic Research 2020.